As previously highlighted in Trends, there are nearly endless opportunities to leverage technology in order to deploy more precise, efficient, and impactful interventions at exactly the right moments in a patient’s care. Increasingly, artificial intelligence is poised to be the engine that drives these cost-effective improvements across the care continuum. However, the emotional, life and death aspect of health care makes its technological transformation very different from that of most industries. What institutional hurdles will have to be overcome before AI can realize its potential in health care? What can be done to address these hurdles? And what are the implications for the industry, for public policy, and for our quality of life? We’ll provide the answers you need.